Mitigating Severe Hypoglycemia by Initiating Inpatient Continuous Glucose Monitoring for Type 1 Diabetes Mellitus.

 Continuous glucose monitoring for type 1 diabetes mellitus will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, comparators, and outcomes, will be further developed in the refinement phase.  When key questions have been drafted, they will be posted on the AHRQ Web site and open for public comment. To sign up for notification when this and other Effective Health Care (EHC) Program topics are posted for public comment, please go to Nomination Summary: The nominator is interested in the comparative effectiveness of various treatment strategies with and without continuous glucose monitoring for type 1 diabetes on HbA1c values. The nominator suggests that many patients benefit from continuous glucose monitoring with daily insulin injections or insulin pump therapy; however, insurance coverage is limited to private insurance companies. The nominator asserts that variations in insulin needs can be closely monitored and recorded with continuous glucose monitoring, which may lead to improved insulin dosing and better glucose control. Staff-Generated PICO: Population(s): Adults and children with type 1 diabetes mellitus Intervention(s): Multiple daily injections with continuous glucose monitoring or insulin pump therapy with continuous glucose monitoring Comparator(s): Multiple daily injections alone or Insulin pump therapy alone Outcome(s): HbA1c levels Key Questions from Nominator: 1. What are the comparative differences in HbA1c levels when comparing various treatment options including multiple daily injections, insulin pump therapy, daily injections with continuous glucose monitoring, and insulin pump therapy with continuous glucose monitoring?